Couple-close construction of polycyclic rings from diradicals

Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07181-xA couple-close approach used to build semisaturated ring systems from dual radical precursors allows sampling of regions of underexplored chemical space, leading to an annulation that can be used for late-stage functionalization of pharmaceutical scaffolds.

  Nature & & science   Mar 13, 2024   0   62  Add to Reading List
Couple-close construction of polycyclic rings from diradicals

Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07181-x

A couple-close approach used to build semisaturated ring systems from dual radical precursors allows sampling of regions of underexplored chemical space, leading to an annulation that can be used for late-stage functionalization of pharmaceutical scaffolds.
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