IL-10 constrains sphingolipid metabolism to limit inflammation

Nature, Published online: 21 February 2024; doi:10.1038/s41586-024-07098-5IL-10 exerts its anti-inflammatory activity in macrophages by increasing the expression of enzymes that promote fatty acid desaturation and downstream regulation of the transcription factor REL.

IL-10 constrains sphingolipid metabolism to limit inflammation

Nature, Published online: 21 February 2024; doi:10.1038/s41586-024-07098-5

IL-10 exerts its anti-inflammatory activity in macrophages by increasing the expression of enzymes that promote fatty acid desaturation and downstream regulation of the transcription factor REL.

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