B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4

Nature, Published online: 21 February 2024; doi:10.1038/s41586-024-07079-8The immune system is tolerized against the neuromyelitis optica autoantigen AQP4 by thymic B cells, which present their endogenous AQP4 to AQP4-reactive thymocytes.

  Nature & & science   Feb 25, 2024   0   59  Add to Reading List
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4

Nature, Published online: 21 February 2024; doi:10.1038/s41586-024-07079-8

The immune system is tolerized against the neuromyelitis optica autoantigen AQP4 by thymic B cells, which present their endogenous AQP4 to AQP4-reactive thymocytes.
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