AIRE relies on Z-DNA to flag gene targets for thymic T cell tolerization

Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07169-7Z-DNA anchors the AIRE-mediated transcriptional program by enhancing the generation of double-stranded breaks and promoter poising.

  Nature & & science   Mar 13, 2024   0   43  Add to Reading List
AIRE relies on Z-DNA to flag gene targets for thymic T cell tolerization

Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07169-7

Z-DNA anchors the AIRE-mediated transcriptional program by enhancing the generation of double-stranded breaks and promoter poising.
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