Evolutionary trajectories of small cell lung cancer under therapy

Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07177-7We uncover key processes of the genomic evolution of small cell lung cancer under therapy, identify the common ancestor as the source of clonal diversity at relapse and show central genomic patterns associated with drug response.

Evolutionary trajectories of small cell lung cancer under therapy

Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07177-7

We uncover key processes of the genomic evolution of small cell lung cancer under therapy, identify the common ancestor as the source of clonal diversity at relapse and show central genomic patterns associated with drug response.

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