SOX17 enables immune evasion of early colorectal adenomas and cancers

Nature, Published online: 28 February 2024; doi:10.1038/s41586-024-07135-3Transcriptomic and chromatin accessibility analyses of naive and transplanted colon cancer organoids in a mouse model reveal a key role for the transcription factor SOX17 in establishing a permissive immune environment for tumour cells.

SOX17 enables immune evasion of early colorectal adenomas and cancers

Nature, Published online: 28 February 2024; doi:10.1038/s41586-024-07135-3

Transcriptomic and chromatin accessibility analyses of naive and transplanted colon cancer organoids in a mouse model reveal a key role for the transcription factor SOX17 in establishing a permissive immune environment for tumour cells.

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