Mechanisms of action and resistance in histone methylation-targeted therapy

Nature, Published online: 21 February 2024; doi:10.1038/s41586-024-07103-xThe mechanisms of action and resistance of valemetostat, an EZH1–EZH2 dual inhibitor, in patients with adult T cell leukaemia/lymphoma who initially responded but later showed disease progression are explored.

  Nature & & science   Feb 25, 2024   0   43  Add to Reading List
Mechanisms of action and resistance in histone methylation-targeted therapy

Nature, Published online: 21 February 2024; doi:10.1038/s41586-024-07103-x

The mechanisms of action and resistance of valemetostat, an EZH1–EZH2 dual inhibitor, in patients with adult T cell leukaemia/lymphoma who initially responded but later showed disease progression are explored.
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