Dopamine receptor D2 confers colonization resistance via microbial metabolites

Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07179-5In a mouse model of enteric pathogen infection, tryptophan metabolites protect against infection via activation of dopamine receptor D2 and regulation of actin cytoskeletal organization in intestinal epithelial cells.

  Nature & & science   Mar 13, 2024   0   43  Add to Reading List
Dopamine receptor D2 confers colonization resistance via microbial metabolites

Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07179-5

In a mouse model of enteric pathogen infection, tryptophan metabolites protect against infection via activation of dopamine receptor D2 and regulation of actin cytoskeletal organization in intestinal epithelial cells.
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