APOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microglia

Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07185-7A microglial state, featuring lipid droplets and secretion of neurotoxic factors, is shown to be most prominent in people with Alzheimer’s disease who have the APOE4 genotype.

APOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microglia

Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07185-7

A microglial state, featuring lipid droplets and secretion of neurotoxic factors, is shown to be most prominent in people with Alzheimer’s disease who have the APOE4 genotype.

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